Diosmetin alleviates benzo[a]pyrene-exacerbated H1N1 influenza virus-induced acute lung injury and dysregulation of inflammation through modulation of the PPAR-γ-NF-κB/P38 MAPK signaling axis

Diosmetin suppressed the enhanced pro-inflammatory response and apoptosis via inhibition of the augmentation of NF-κB and P38 kinase activation in a PPAR-γ-dependent manner, facilitating the alleviation of B[ a ]P-exacerbated H1N1 virus-induced respiratory illness.