Epileptiform discharges, electrographic seizures, and electroclinical seizures during paediatric sevoflurane anaesthesia. Response to Br J Anaesth 2023; 130: e423–e424

Editor—We thank Miao and colleagues1 for their comment on our systematic review2 in the British Journal of Anaesthesia, and acknowledge their interesting work studying epileptiform EEG discharges during paediatric sevoflurane anaesthesia.3 The central thesis of our study was that the high degree of heterogeneity between published studies, particularly in the inconsistent or unconventional EEG outcome definitions used for classifying abnormal EEG changes, make it difficult to pool data from different studies for meta-analysis.