常用化疗药物
化疗
药品
药物输送
医学
药理学
临床试验
癌症
肿瘤科
纳米技术
内科学
材料科学
作者
Lingling Yan,Jingjing Shen,Jinqiao Wang,Xiaoyan Yang,Shiyan Dong,Saijun Lu
出处
期刊:Dose-response
[SAGE]
日期:2020-07-01
卷期号:18 (3): 155932582093616-155932582093616
被引量:89
标识
DOI:10.1177/1559325820936161
摘要
Chemotherapy is widely used to treat cancer. The toxic effect of conventional chemotherapeutic drugs on healthy cells leads to serious toxic and side effects of conventional chemotherapy. The application of nanotechnology in tumor chemotherapy can increase the specificity of anticancer agents, increase the killing effect of tumors, and reduce toxic and side effects. Currently, a variety of formulations based on nanoparticles (NPs) for delivering chemotherapeutic drugs have been put into clinical use, and several others are in the stage of development or clinical trials. In this review, after briefly introducing current cancer chemotherapeutic methods and their limitations, we describe the clinical applications and advantages and disadvantages of several different types of NPs-based chemotherapeutic agents. We have summarized a lot of information in tables and figures related to the delivery of chemotherapeutic drugs based on NPs and the design of NPs with active targeting capabilities.
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