Research progress about the effect of portal vein pressure on liver regeneration

The occurrence of small liver syndrome and liver failure is still a serious complication that threatens the survival of patients after small liver transplantation or extended liver resection. Therefore, it is very important to understandthe mechanism of liver regeneration after operation and look for effective ways to promote liver regeneration. Many experiments have confirmed that changes in portal venous pressure (PVP) may be necessary to initiate and maintain liver regeneration processes and even terminate liver regeneration. This article reviews the recent research progress about the effect of PVP on liver regeneration. Key words: Liver regeneration; Portal pressure; Hepatectomy; Liver transplantation