Composite Enhancement Polyether-Ether-Ketone for Long Segmental Spinal Column Deformity Orthopedic Treatment

偷看 材料科学 接触角 聚醚醚酮 石墨烯 复合材料 拉曼光谱 脊柱融合术 扫描电子显微镜 外科 纳米技术 聚合物 医学 光学 物理
作者
Qingjun Mao,Jixiang Wang,Xiaofeng Song,Haipeng Pang,Yao-Hua Tao,Jianping Cai,Jie Li,Yuguang Song
出处
期刊:Science of Advanced Materials [American Scientific Publishers]
卷期号:12 (9): 1332-1340
标识
DOI:10.1166/sam.2020.3820
摘要

Polyether-ether-ketone (PEEK) anterior intervertebral fusion combined with posterior long segment orthopedic surgery is a common method for the therapy of orthopedic deformity of the spine. PEEK material plays an important role in the effect of surgery. Graphene on copper substrate was transferred to the surface of carbon-fiber reinforced polyether-ether-ketone (CFR-PEEK) material by ferric chloride (FeCl 3 ) chemical erosion and physical adsorption, hence the compound enhancement polyether-ether-ketone (Ge-PEEK) was achieved. In terms of characterization, Raman spectrometer was used to analyze the characteristics of the product generation, the scanning electron microscope (SEM) was used to analyze the morphology of the product, and the hydrophilicity of the material was analyzed by the droplet contact Angle. From the perspective of intervertebral fusion, Ge-PEEK material was used in the intervertebral fusion device to analyze the effect of the fusion device in the correction of spinal deformity, such as displacement, convex Angle, and collapse. In the characterization test, Raman spectrum analysis showed that Ge-PEEK material had the characteristic peaks of graphene, and SEM analysis showed that CFR-PEEK material was covered on a large scale by graphene. In the droplet contact angle test, the contact angle of the graphene-modified CFR-PEEK material was significantly reduced ( P < 0.05). The material had good hydrophilicity. In the analysis of lumbar interfusion, the anterior intervertebral fusion rate based on Ge-PEEK material was 95.8% ( P < 0.05), and the vertebral deposition rate based on Ge-PEEK fusion device was 7.2% ( P < 0.05). At the same time, the distance between the leading edge of the cone after operation and the last follow-up was compared, and it was found that the displacement distance of different segments was smaller ( P < 0.05). This study proved that the proposed Ge-PEEK material was feasible for anterior intervertebral fusion in the correction of long-segment spinal deformity.

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