Case Study Of Cryoglobulinemia

Cryoglobulinemia is one of rare disorders characterised by presence of cryoglobulins( abnormal proteins)in the blood. Cryoglobulins clump together at cold temperatures, usually below 98.6degree Fahrenheit. The cause varies from person to person. Some of the most common causes include having an abundance of cryoglobulin in blood. To reve about this rare disorder, skin biopsy is done, Renal disease may occur secondary to thrombosis (type I cryoglobulinemia) or immune complex deposition (types II and III). The incidence of renal disease varies from 5-60%. Histologically, membranoproliferative glomerulonephritis is almost always the lesion in  cryoglobulinemia.