小胶质细胞
冲程(发动机)
神经科学
免疫系统
促炎细胞因子
药品
医学
机制(生物学)
中枢神经系统
药物作用
炎症
免疫学
药理学
心理学
机械工程
哲学
认识论
工程类
作者
Ling‐Jing Zhang,Huijie Zhou,Shi‐Ya Wang,Yi‐Huan Guan,Chao Zhang,Derong Fang
出处
期刊:Ibrain
日期:2022-05-22
卷期号:8 (2): 227-240
摘要
Microglia are the main immune cells in the brain and the first defense barrier of the nervous system. Microglia play a complex role in the process of stroke. A growing number of studies focus on the mechanism of action of drugs functions and how to regulate microglia. Therefore, we talk about the pathophysiological mechanisms of stroke and elaborate on the microglia signaling pathways of drug action in stroke models and how these drugs play a role in stroke treatment in this review. Understanding how drugs modulate proinflammatory and anti-inflammatory responses of microglia may be critical to implementing therapeutic strategies using immune interventions in stroke.
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