Enamel matrix derivative and periodontal tissue regeneration

The main component of Emdogain is the enamel matrix derivative(EMD) extracted from porcine tooth buds by acidic extraction and purified by chromatography.EMD can not only induce the regeneration of acellular cement,but also promote the proliferation and differentiation of periodontal ligament cells.In recent years,researches on the role of EMD in periodontal tissue regeneration have become a hot spot in periodontics.This article offers an overview on the recent studies on the effects of EMD in periodontal tissue regeneration and its application in clinical stomagology.