Applied advances of 5-aminolevulinic acid photodynamic therapy in dermatology

To explore the mechanism and application of photodynamic therapy using aminolevulinic acid (5-ALA) in skin diseases, and provide reference for the rational use in clinic. Summarize the reported articles of mechanism and clinical application of photodynamic therapy in recent ten years, analysis the mechanism in the photodynamic therapy treatment for various skin disease, sort the types of skin disease cured by photodynamic therapy and the side effect related with photodynamic therapy. Photodynamic therapy have good clinical curative effect in skin cancer, erythema scaly skin neoplasms, psoriasis, viral warts, acne, nevus flammeus, etc. and have fewer adverse reactions. Photodynamic therapy is a safe, efficient treatment of psoriasis, and have great application prospects in skin diseases.