Application of gastroscopy for children with helicobacter pylori-related gastritis

objective To evaluate clinical application for children with helicobacter pylori-related gastritis.Methods 132 children with gastritis were assigned into 3 groups: group A(children with HP-related gastritis);group B(children with Hp negative gastritis);groupC(children uncooprative to gastroscopy).Each group received the same basic treatment,besides group A received normal triple theraphy for anti-Hp.In each group,gastrocopy results and mucosal histopathological changes before and 4 weeks,6-12 months after treatment were observed.Resoult 4 weeks after treatment,the effective rates of abdominal pain and epigastrium tenderness in group A were 92.16 %(47/51) and 94.12 %(48/51);in group B,they were 88.89 %(8/9) and 88.89 %(8/9);in group C,they were 16.67 %(11/66) and 13.64(9/66).Group A had significant differences with group B and group C(χ2 =(70.91),71.54,P(0.05)).The follow-up of 6-12 months indicated that 47 cases(47/51) were with successive negative –Hp in group A,inflammation was controlled,inflammation degree in group B after theraphy was less than those before treatment(P (0.01)).Conclusion Gastroscopy is an important means to diagnose helicobacter pylori-related gastritis in children.