Recent advancement of succinate dehydrogenase inhibitors based on the natural product scaffold

Abstract In face of large-scale plant diseases, the control of chemical pesticides remained a fast, economical and effective method. The search for novel bioactive pesticide has long been a priority in crop protection for solve the plant pathogen resistance. Natural products and their derivatives have been the major sources of the discovery of novel fungicides. Succinate dehydrogenase inhibitors (SDHIs) fungicides are the third largest category of fungicides. Meanwhile, the resistance of SDHIs with plant pathogen had been an urgent problem. It was an effective way to delay the resistance problem by the creation of fungicides from natural product. Considering these issues, here we have reviewed the published articles on the SDHIs fungicides during past five years (2020–2024) based on three kinds of natural product scaffolds.