疾病
变硬
流行病学
心血管健康
入射(几何)
风险因素
生物
心力衰竭
老年学
医学
生物信息学
病理
内科学
工程类
土木工程
物理
光学
作者
Shria Moturi,Shohini Ghosh-Choudhary,Toren Finkel
标识
DOI:10.1016/j.yjmcc.2022.04.005
摘要
The incidence and prevalence of a wide range of cardiovascular diseases increases as a function of age. This well-established epidemiological relationship suggests that chronological aging might contribute or increase susceptibility to varied conditions such as atherosclerosis, vascular stiffening or heart failure. Here, we explore the mechanistic links that connect both rare and common cardiovascular conditions to the basic biology of aging. These links provide a rational basis to begin to develop a new set of therapeutics targeting the fundamental mechanisms underlying the aging process and suggest that in the near future, age itself might become a modifiable cardiovascular risk factor.
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