Application of Nanomagnetic NH 2 .MIL-101(Fe)/ED as a Retrievable and Efficient Catalyst for the Synthesis of 2,6-Diamino-4-Aryl-4H-Thiopyran- 3,5- Dicarbonitrile Derivatives

Abstract In this publication, we reported an efficient one-pot, four-component procedure for the synthesis of 2,6-diamino-4-Aryl-4 H -Thiopyran-3,5-dicarbonitrile derivatives by a reaction between primary amines, carbon disulfide, malononitrile, and benzylidenemalononitrile in the presence of magnetic NH 2 .MIL-101(Fe)/ED as a basic metal organic framework catalyst. Magnetic NH 2 .MIL-101(Fe)/ED was synthesized through anchoring FeCl 3 on CoFe 2 O 4 magnetic nanoparticles surface and then 2-aminoterphthalic acid was used to form MOF structure. At the final step, metal centers were modified with ethylenediamine (ED). The different techniques such as Fourier transmission infrared spectroscopy, X-ray diffraction, Field emission scanning electron microscopy, Transmission electron microscopy, Brunauer-Emmett-Teller analysis, and Thermogravimetric analysis were used to characterize the structure of the catalyst. Using X-ray crystallography, the structure of the final product was also determined.