Microanatomy of the Central Myelin-peripheral Myelin Transition Zone of the Trigeminal Nerve

In Reply: We thank Drs. Ziyal and Özgen for their Letter to the Editor regarding our article, “Microanatomy of the Central Myelin-peripheral Myelin Transition Zone of the Trigeminal Nerve” (1). We are aware of their article, which is also referred to in our study. In our study, we examined 100 trigeminal nerves obtained from cadavers. The results of our study correspond with the largest anatomical study in the literature. In the study by Ziyal et al. (2), the authors histopathologically examined only six trigeminal nerves. In one of the figures accompanying their study, the shape of the transitional zone seems to mimic a Scandinavian fiord. However, the shape of the transitional zone in the other specimen they show is sharp. We do agree with the authors that, of the treatment options for trigeminal neuralgia, microvascular decompression shows a high rate of cure. However, we are not sure how this surgery helps to relieve the symptoms of this disease. Selçuk Peker M. Necmettin Pamir Istanbul, Turkey