新皮层
鼻周皮质
颞叶
神经科学
记忆的神经解剖学
海马体
长期记忆
失忆症
情景记忆
内嗅皮质
识别记忆
心理学
认知心理学
外显记忆
认知
癫痫
作者
Larry R. Squire,Stuart Zola‐Morgan
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:1991-09-20
卷期号:253 (5026): 1380-1386
被引量:2930
标识
DOI:10.1126/science.1896849
摘要
Studies of human amnesia and studies of an animal model of human amnesia in the monkey have identified the anatomical components of the brain system for memory in the medial temporal lobe and have illuminated its function. This neural system consists of the hippocampus and adjacent, anatomically related cortex, including entorhinal, perirhinal, and parahippocampal cortices. These structures, presumably by virtue of their widespread and reciprocal connections with neocortex, are essential for establishing long-term memory for facts and events (declarative memory). The medial temporal lobe memory system is needed to bind together the distributed storage sites in neocortex that represent a whole memory. However, the role of this system is only temporary. As time passes after learning, memory stored in neocortex gradually becomes independent of medial temporal lobe structures.
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