补体系统
获得性免疫系统
免疫学
CD59型
先天免疫系统
生物
CD46型
免疫系统
补语(音乐)
补体受体
衰变加速因子
免疫
细胞生物学
基因
表型
遗传学
互补
作者
M. Paula Longhi,Claire L. Harris,B. Paul Morgan,Awen Gallimore
标识
DOI:10.1016/j.it.2005.12.008
摘要
Complement is not only part of the innate immune system, but has also been implicated in adaptive immunity. The role of complement and its regulatory proteins in modulating T cell activity has been the focus of several recent studies. These, which have included work on the membrane co-factor protein (MCP or CD46), decay accelerating factor (DAF or CD55) and CD59, indicate that complement regulators can influence the proliferative capacity of T cells and their ability to produce cytokines, influencing the outcome of a T cell response to a given antigen. Here we review these studies, which reveal another important link between the innate and the adaptive immune system.
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