To screen a germ which has significant antagonism against wheat Fusarium head blight and to find an effective biological method to control it,endogenous antagonistic bacteria from Fujian province were analyzed.The results showed that five strains were Bacillus spp.and they had antagonistic effects on Fusarium graminearum,of which strains of JY1-9,JY1-3 inhibition was significantly higher than the other three strains.It was suggested that strains JY1-9 and JY1-3 had the potentiality in biological control of wheat Fusarium head blight.