Objective To evaluate the clinical efficacy of the percutaneous kyphoplasty for osteoporotic Kummell's disease. Methods A total of 18 patients with osteoporotic Kummell's disease underwent percutaneous balloon kyphoptasty from January 2007 to June 2012. There were 6 males and 12 females with the mean age of 69. 5 years( range 62 to 86 years). All patients underwent back pain for 3. 5 months( from 1 month to 3 years). The involved segment sagittal Cobb's angle was measured pre- and postoperatively(2 d after the operation) and at the final follow-up. The visual analog scale( VAS) and Oswestry disability index(ODI) were used to evaluate pain and function. Results Patients were followed up 12-36 months.The pain relieved in all patients. Cobb's angle improved from preoperative average 32. 60° ± 3. 82° to postoperative 7. 60° ±1. 68°,VAS scores and ODI were improved from an average of 8. 7 points,88. 6% before surgery to a postoperative average2. 6 points,28. 6%. The differences was statistically significant(P 0. 01); Cobb's angle average was 9. 60° ± 2. 06 ° and VAS was 2. 2 scores and ODI was 26. 4 % at the final follow-up respectively,compared with 2 d postoperative,the difference was not statistically significant( P 0. 05). Conclusion With hyperextension body postures,the percutaneous vertebral kyphoplasty is an effective method for the treatment of osteoporosis Kummell's disease.