The Relationship Between Tetrahydrobiopterin and Endothelial Dysfunction

Endothelial function disorder exists in many cardiovascular diseases,which may come from the decrement of nitric oxide.Tetrahydrobiopterin is a kind of essential cofactor of nitric oxide synthase,which can regulate nitric oxide synthase function and activity of nitric oxide.This article reviews the usefulness of tetrahydrobiopterin in cardiovascular diseases.