Effect of Different Extraction Methods on the Chemical Components of Volatile Oil from Ligusticum chuanxiong

[Objective] The aim was to discuss the effect of different extraction method on chemical components of volatile oil of Ligusticum chuanxiong.[Method] The L.chuanxiong oil were extracted by 3 kinds of methods of supercritical fluid extraction,steam distillation and neutral alcohol extract method,and its contained chemical components and its relative content were separated and identified by GC-MS combined with calculation technology.[Result] There were 16 same components in the volatile oil extracted by 3 kinds of methods of supercritical fluid extraction,steam distillation and neutral alcohol extract method,which counted for 79.87%,89.42% and 71.32% of their relative content,resp..Among them,10,8 and 5 components were their specific,which counted for 2.51%,3.03% and 6.90%.The 3 kinds of technics all could extract the main components of volatile oil,lactone components and among them,the contained components of samples extracted by supercritical fluid CO2 extraction were most and the whole operation process spent short time and had high efficiency.[Conclusion] The research provided the basis for the development of medicinal resources of L.chuanxiong and selection of processing process.