Diosgenin,an important steroid sapogenin,is one of major precursors of synthetic steroids.It is rich in natural resources and has various significant activities such as anti-tumor,anti-inflammation,and cardiovascular-protection and so on.Recently,it causes increasing attention of scholars all over the world due to its valuable application in medicine.In this paper,the latest international research advances of diosgenin in its pharmacologic activities and mechanism were reviewed.