羰基化
化学
烷氧基
有机化学
催化作用
碳二亚胺
硼酸
化学选择性
组合化学
一氧化碳
烷基
作者
Chang‐Sheng Kuai,Bing-Hong Teng,Yingying Zhao,Xiao‐Feng Wu
标识
DOI:10.1016/j.jcat.2023.06.012
摘要
A method for the chemodivergent deoxygenative- and alkoxy-carbonylation of alcohols with boronic acids via palladium catalysis has been developed. Manipulation of the divergent selectivities depend on simply changing the choice of activators. While a carbodiimide activator promoted the formation of ketones through deoxygenative carbonylation, selectivity for esters via alkoxy carbonylation was observed with an azo activator. Notably, in addition to the broad substrate scope, this base-free strategy enables the use of highly base-sensitive boronic acid substrates. This study contributes to the art of chemoselectivity control in carbonylation chemistry.
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