溶菌酶
羊毛
抗菌活性
化学
二硫化钼
抗菌肽
纳米材料
二硫键
光热效应
金黄色葡萄球菌
纳米技术
光热治疗
生物物理学
化学工程
核化学
细菌
生物化学
材料科学
复合材料
生物
工程类
遗传学
作者
Ning Zhang,Rongjin Shi,Man Zhou,Ping Wang,Yuanyuan Yu,Qiang Wang
标识
DOI:10.1016/j.ijbiomac.2023.125699
摘要
Textiles with efficient and long-lasting antibacterial properties have attracted significant attention. However, a single antibacterial model is insufficient to with variable environments and achieve higher antibacterial activity. In this study, lysozyme was used as assistant and stabilizer, and the efficient peeling and functional modification of molybdenum disulfide nanosheets were realized by ultrasonic. Additionally, lysozyme in the presence of reducing agents to form amyloid-like phase-transited lysozyme (PTL) and self-assembling on the wool fabric. Finally, the AgNPs are reduced in situ by PTL and anchored onto the fabric. It has been demonstrated that Ag-MoS2/[email protected] generates ROS under light irradiation, rapidly converts photothermal heat into generate hyperthermia, and promotes the release of Ag+. The aforementioned “four-in-one” approach resulted in bactericidal rates of 99.996 % (4.4 log, P < 0.0005) and 99.998 % (4.7 log, P < 0.0005) for S.aureus and E.coli, respectively. Even after 50 washing cycles, the inactivation rates remained at 99.813 % and 99.792 % for S.aureus and E.coli, respectively. In the absence of sunlight, AgNPs and PTL continue to provide continuous antibacterial activity. This work emphasizes the importance of amyloid protein in the synthesis and application of high-performance nanomaterials and provides a new direction for the safe and effective application of multiple synergistic antibacterial modes for microbial inactivation.
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