Cell-free and cytokine-free self-assembling peptide hydrogel-polycaprolactone composite scaffolds for segmental bone defects

An ECM-mimetic peptide hydrogel was infilled into a 3D-printed PCL scaffold, forming unique nano- and micro-morphology and endowing osteogenesis. This scaffold was employed for a segmental ulna defect repair in rabbits, with bioinformatic analysis.