糖尿病肾病
纤维化
医学
肾病
内科学
糖尿病
肾
泌尿科
内分泌学
作者
Xiaofang Hu,Wei Chen,Ming Yang,Mengwei Li,Xiangyi Li,Shaxi Ouyang
标识
DOI:10.1007/s00018-025-05718-5
摘要
IGFBP5 promotes NLRP3 inflammasome-induced EndoMT and renal fibrosis by regulating glycolysis-mediated histone lactylation, accelerating the progression of DN. These findings provide a new potential therapeutic target for DN.
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