Cooperative N-heterocyclic carbene/photocatalysis: visible-light-promoted tandem α-sp3 C–H activation and reductive N-alkylation of tetrahydroisoquinoline

Visible-light mediated, NHC-catalyzed tandem α-sp 3 C–H activation & reductive N -alkylation of tetrahydroisoquinoline was reported. The reaction proceeds via deprotonated o -hydroxybenzaldehydes as self-photocatalyst in presence oxygen and sunlight.