粒体自噬
兰克尔
糖尿病
细胞生物学
组织重塑
心室重构
糖尿病性心肌病
线粒体
自噬
医学
内科学
信号转导
心房肌细胞
内分泌学
心房颤动
癌症研究
线粒体ROS
受体
心力衰竭
作者
Lu Zhou,Daiqi Liu,Qiankun Bao,Zandong Zhou,Ziheng Jia,Xinyi Gao,Wenhua Song,Gary Tse,Gregory Y.H. Lip,Tong Liu,Qingmiao Shao
标识
DOI：10.1016/j.cellsig.2025.112148
摘要
In atrial myocytes, mitophagy is mediated by the LRRc17-RANKL pathway. Diabetes induced atrial remodeling may worsen due to the overexpression of RANKL brought on by the decrease in LRRc17. The LRRc17-RANKL pathway may be a therapy option for diabetic atrial remodeling by improving mitochondrial function.
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(2025-6-4)
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