肠道菌群
肠道微生物群
生物
人体研究
微生物群
生物信息学
免疫学
医学
内科学
作者
Jacco J.A.J. Bastings,Koen Venema,Ellen E. Blaak,Tanja C. Adam
标识
DOI:10.1016/j.tem.2023.02.003
摘要
Recent studies show a link between the gut microbiota and the regulation of satiety and energy intake, processes that contribute to the development and pathophysiology of metabolic diseases. However, this link is predominantly established in animal and in vitro studies, whereas human intervention studies are scarce. In this review we focus on recent evidence linking satiety and the gut microbiome, with specific emphasis on gut microbial short-chain fatty acids (SCFAs). Based on a systematic search we provide an overview of human studies linking the intake of prebiotics with gut microbial alterations and satiety signaling. Our outcomes highlight the importance of in-depth examination of the gut microbiota in relation to satiety and provide insights into recent and future studies in this field.
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