Inflammatory Pseudotumor of Intestine Mimicking Lymphoma on 18F-FDG PET/CT

A 45-year-old man with suspected colonic malignancy was referred to F-FDG PET/CT for staging. PET/CT images showed segmental increased FDG uptake along the intestine with thickening of colonic wall, where no mass was obviously seen. Subsequently, left hemicolectomy and resection of partial small intestine were done. Histopathology of the resected specimen confirmed the diagnosis of inflammatory pseudotumor involving colon and small intestine. No recurrence was detected on follow-up CT images after 6 months. Although most of the previously reported intestinal inflammatory pseudotumor manifested as a mass, it should be considered as a differential diagnosis of FDG-avid segmental intestinal wall thickening.