Inhibition of NLRP3 inflammasome activation and pyroptosis with the ethyl acetate fraction ofBungeanumameliorated cognitive dysfunction in aged mice

A schematic illustration of the research. The ethyl acetate active fraction of Bungeanum ameliorated cognitive deficits in aged mice, and its effects may be related to ameliorating oxidative stress and suppressing the NLRP3 inflammasome pathway and GSDMD-mediated pyroptosis.