化学
卡宾
催化作用
醛
苯
组合化学
有机化学
反应条件
作者
Jichang Wu,Chengli Mou,Yonggui Robin
标识
DOI:10.1002/cjoc.201700773
摘要
A carbene‐catalyzed ester activation reaction for the synthesis of multi‐substituted benzenes is developed. Tetra‐substituted benzene compounds are efficiently synthesized through this methodology. Compared with aldehyde substrates used in previous reports, the ester substrates used here are much more readily available and inexpensive. In addition, the TEMPO oxidant used here is more inexpensive than the quinones commonly used in related carbene‐catalyzed reactions.
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