医学
内分泌学
吉特尔曼综合征
醛固酮
内科学
巴特综合征
上皮钠通道
重吸收
假性低醛固酮血症
代谢性碱中毒
巴特综合征
远曲小管
低钾血症
肾钠重吸收
盐皮质激素
碱中毒
钠
病理生理学
管状流体
盐皮质激素受体
肾
酸中毒
化学
低镁血症
镁
有机化学
作者
Elizabeth Mumford,Robert J. Unwin,Stephen B. Walsh
摘要
ABSTRACT Hypokalaemia with alkalosis can suggest excess aldosterone. Aldosterone stimulates the collecting duct mineralocorticoid receptor (MR) to upregulate the epithelial sodium channel (ENaC) and stimulate electrogenic sodium reabsorption, with secretion of potassium and protons. Gitelman, Bartter and Liddle syndrome, and liquorice ingestion all cause hypokalaemic alkalosis. This mini-review outlines the pathophysiology of these conditions as well as how to differentiate them.
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