MRI Probes: Timely Visualization of the Collaterals Formed during Acute Ischemic Stroke with Fe3O4 Nanoparticle‐based MR Imaging Probe (Small 23/2018)

In article number 1800573 by Xin Lou and co-workers, an αvβ3-specific Fe3O4-RGD nanoprobe is prepared for in vivo magnetic resonance imaging of the collaterals after cerebral ischemia, and shows the binding specificity to the cerebral collaterals. The direct observation of cerebral collaterals is enabled in a quasi-real time fashion, and further studies are also performed to show the collateral dynamics upon reperfusion, which is significantly meaningful for clinical treatment of stroke.