褪黑素
光污染
昼夜节律
松果体
养生
癌变
生理学
内科学
内分泌学
乳腺癌
癌症
生物
医学
肿瘤科
光学
物理
出处
期刊:Neuroendocrinology Letters
日期:2006-02-01
卷期号:27 (1-2): 35-52
被引量:23
摘要
At present, light pollution (exposure to light-at-night) both in the form of occupational exposure during night work and as a personal choice and life style, is experienced by numerous night-active members of our society. Disruption of the circadian rhythms induced by light pollution has been associated with cancer in humans. There are epidemiological evidences of increased breast and colon cancer risk in shift workers. An inhibition of the pineal gland function with exposure to the constant light (LL) regimen promoted carcinogenesis whereas the light deprivation inhibits the carcinogenesis. Treatment with pineal indole hormone melatonin inhibits carcinogenesis in pinealectomized rats or animals kept at the standard light/dark regimen (LD) or at the LL regimen. These observations might lead to use melatonin for cancer prevention in groups of humans at risk of light pollution.
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