Use of antidepressants in smoking cessation treatment: Bupropion -

Smoking remains to be the major preventable cause of early mortality and morbidity. At least 70% of the smokers who quit smoking don't succeed despite the use of the best nicotine replacement treatment (NRT) with behavior treatment. Findings that there is an increased prevalence of depression among smokers and that smokers with depression, have greater difficulty quitting than those without depression led to the investigation of antidepressants as aids for smoking cessation. The aim of this review is to explore the research literature for treating nicotine dependence with antidepressants. Bupropion, which seems to be effective in smoking cessation treatment, reduces withdrawal symptoms and weight gain, which occurs after quiting smoking, and throughout out the treatment. With these properties, bupropion comes in view as a useful treatment intervention in smoking cessation.