[Current Status and Progress of Thermal Ablation Combined with Immunotherapy for Lung Tumors].

免疫疗法 医学 肿瘤微环境 肺癌 放射治疗 热烧蚀 微波消融 免疫系统 烧蚀 肺肿瘤 癌症 癌症免疫疗法 癌症研究 肿瘤科 内科学 免疫学
作者
Baodong Liu
出处
期刊:PubMed 卷期号:25 (4): 266-271 被引量:1
标识
DOI:10.3779/j.issn.1009-3419.2022.102.09
摘要

Recent studies have shown that tumor immune microenvironment is closely related to tumor progression, metastasis, recurrence and response to treatment. Some immunotherapies also offer hope for cancer patients. However, the efficacy of tumor immunotherapy is uncertain and has some side effects. In order to enhance its efficacy, tumor immunotherapy combined with tumor thermal ablation has been studied. Thermal ablation has the advantages of minimally invasive, rapid recovery, safety, fewer complications, conformation, reliable effect, repeatable, low cost, and has become the fourth tumor treatment measure after surgery, radiotherapy, and drug therapy. It can directly kill tumor cells and modulate the immune system through a variety of mechanisms, although the corresponding mechanisms are not well understood, but combined tumor immunotherapy has been proposed to treat several solid malignancies. In this review, the current status and progress of thermal ablation combined with immunotherapy for lung tumor were reviewed, and further studies on the efficacy and safety of thermal ablation combined with immunotherapy were expected. .

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