Prospective Randomized Controlled Study on Treatment of Stage T1-3N0M0 Middle-Lower Section Esophageal Cancer by Two Minimally Invasive Radical Surgeries

Objective: to conduct contrastive analysis of treatment effect of peritoneoscope plus intrathoracic anastomosis for esophageal cancer resection (Ivor-Lewis surgery) and peritoneoscope plus neck anastomosis for esophageal cancer resection (McKeown surgery) on Stage T1-3N0M0 middle-lower section esophageal cancer.Method: the research period is from January 1, 2015 to December 31, 2017.The research objects include 100 patients with Stage T1-3N0M0 middle-lower section esophageal cancer.They were classified into Ivor-Lewis group (50 cases, treatment with Ivor-Lewis surgery) and McKeown group (50 cases, treatment with McKeown surgery) with random number table.Conventional surgical indexes of patients, surgical index, QLQ-OES18 and postoperative complications were compared and analyzed.Results: the surgery duration, intraoperative blood loss volume, lymph node dissection quantity, and average hospital stay had no significant differences in both groups, and there was no statistical significance (P>0.05).(2) QLQ-C30 3.0 score and QLQ-OES18 score of Ivor-Lewis group were higher than that of McKeown group, and the difference had statistical significance (P<0.05).(3) The total occurrence rate of complications in Ivor-Lewis group was higher than that of McKeown group, and the difference was significant and had statistical significance (P<0.05).Conclusion: for treatment of Stage T1-3N0M0 middle-lower section esophageal cancer, Ivor-Lewis surgery and McKeown surgery have little difference in surgical indexes, but complication occurrence rate of Ivor-Lewis group is low, and the living quality is high.Thus, it can be used as the optimal method to treat Stage T1-3N0M0 middle-lower section esophageal cancer.