Comparison of foam sclerotherapy and cyanoacrylate glue for preventing the recurrence of varicose veins

Background: Varicose veins are a common vascular disorder that can cause discomfort and aesthetic concerns. Cyanoacrylate glue and foam sclerotherapy are treatment modalities used to prevent recurrence of varicose veins, but their comparative effectiveness is not well established. Objective: This research compared the effectiveness of foam sclerotherapy and cyanoacrylate glue in preventing varicose vein recurrence. Methods: A randomized controlled trial was conducted from June to December 2022, including 140 participants equally divided into cyanoacrylate glue and foam sclerotherapy groups. Convenience sampling was employed to recruit participants from clinics and hospitals. Data on demographic characteristics, clinical severity, treatment outcomes, and patient satisfaction were collected and analyzed. Results: In comparison to the foam sclerotherapy group, the cyanoacrylate glue group showed considerably lower recurrence rates (10.7% vs. 14.6%), greater symptomatic recovery (88.9% vs. 82.5%), and higher aesthetic satisfaction (95.3% vs. 90.1%). Patient compliance was higher (94.2%) and pain levels were lower (2.3 out of 10) in the cyanoacrylate glue group. Conclusion: Cyanoacrylate glue treatment showed superior efficacy in preventing varicose vein recurrence, improving symptoms, and enhancing patient satisfaction compared to foam sclerotherapy.