The Role of Gender in Revascularization Strategies for Acute Coronary Syndrome and Multivessel Disease

More than half of patients who present with an acute coronary syndrome (ACS) exhibit multivessel disease (MVD) 1. The benefits of complete revascularization, addressing all coronary lesions, in contrast to culprit lesion-only percutaneous coronary intervention (PCI), are established in hemodynamically stable ACS patients with MVD 2-6. European and American guidelines endorse this approach, with strong supporting evidence for ST-segment elevation myocardial infarction (STEMI) and somewhat less robust evidence for non–ST-segment elevation ACS and cardiogenic shock 7, 8.