等离子体子
纳米技术
拉曼散射
纳米结构
材料科学
等离子纳米粒子
拉曼光谱
胶体金
纳米颗粒
表面等离子共振
接口(物质)
光电子学
光学
物理
毛细管数
毛细管作用
复合材料
作者
Huan Liang,Lingling Jiang,Hongying Li,Jiale Zhang,Ying Zhuo,Ruo Yuan,Xia Yang
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2023-03-14
卷期号:8 (3): 1192-1199
被引量:4
标识
DOI:10.1021/acssensors.2c02574
摘要
Plasmonic nanostructures have a desirable surface-enhanced Raman scattering (SERS) response related to particle spacing. However, precisely controlling the distance of plasmonic nanostructures is still a challenge. DNA has the merit of specific recognition, and flexible modification of functional groups, which can be used to flexibly adjust the gaps between plasmonic nanostructures for improving the stability of SERS. In this paper, DNA-guided gold nanoparticles formed one-dimensional ordered structures and they were self-assembled at the water-oil interface by a bottom-up approach. Notably, an output switching strategy successfully transfers a small amount of target into a large amount of reporter DNA; thereby, Raman probes are captured on the sensing interface and achieve the SERS assay of microRNA 155 (miRNA-155). This study is an exciting strategy for obtaining ordered plasmonic structures and providing surveillance, which is important for the clinical diagnosis of early-stage cancer.
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