脂肪组织
基质血管部分
移植
间质细胞
生物医学工程
生物信息学
计算机科学
计算生物学
医学
生物
外科
病理
内科学
作者
Chongxuan Lu,Junrong Cai,Feng Lu
摘要
Traditional autologous adipose tissue grafting is commonly used for volume augmentation and tissue regeneration. However, the uniform physical and biological properties of fat grafts often lead to suboptimal performance in diverse patient scenarios and multifaceted requirements. Expanding upon the foundations of autologous fat transplantation, we introduce a pioneering approach termed autologous adipose component transplantation. This innovative concept integrates a meticulously designed protocol aimed at converting autologous adipose tissue into a diverse array of adipose components, each characterized by unique physicochemical properties tailored to address specific applications across varied clinical contexts. Through a series of physical methods, adipose tissue can be transformed into an Adipose Matrix Complex (AMC) providing sufficient rigid support, High-Density Fat (HDF) for further filling, Stromal Vascular Fraction (SVF)-gel for small and/or precise injections, and Adipose Collagen Fragment (ACF) for fine wrinkles and/or facial rejuvenation needs. These distinct adipose components possess inherent characteristics that lend themselves to precise and targeted transplantation strategies, catering to the nuanced demands of individual patient needs. The novel adipose tissue fractionation protocol shows great potential in revolutionizing adipose tissue grafting. It offers a new perspective and methodology for more refined and tailored transplantation.
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