模块化设计
计算机科学
转化(遗传学)
肽
计算生物学
纳米技术
化学
生物化学
生物
材料科学
程序设计语言
基因
作者
Zhi Zheng,Yuan Liang,Jingjing Hu,Fan Xia,Xiaoding Lou
标识
DOI:10.1002/chem.202203225
摘要
Abstract The analysis and regulation of proteins are of great significance for the development of disease diagnosis and treatment. However, complicated analytical environment and complex protein structure severely limit the accuracy of their analysis results. Nowadays, ascribing to the editability and bioactivity of peptides, peptide‐based probes could meet the requirements of good selectivity and high affinity to overcome the challenges. In this review, we summarize the advances in the use of modular peptide probes for proteins analysis. It focuses on how to design and optimize the structure of probes, as well as their performance. Then, the strategies and application to improve the analysis result of modular peptide probes are introduced. Finally, we also discuss current challenge and provide some ideas for the future direction for modular peptide probes, hoping to accelerate their clinical transformation.
科研通智能强力驱动
Strongly Powered by AbleSci AI