Efficient electrochemical detection of L-lactic acid using platinum nanoparticle decorated Chitosan/ZnTiO3 nanocomposites

Herein, a facile L-lactic acid electrochemical sensor based on Pt-nanoparticles (NPs)@Chitosan/ZnTiO 3 nanocomposites (NCs) coated on a glassy carbon electrode (GCE) is demonstrated. Ultra-sonication method followed by irradiation using an Osram Hg-lamp was applied to prepare Pt-NPs@Chitosan/ZnTiO 3 NCs, and the characterization of prepared NCs was executed by Field Emission Scanning Electron Microscopy) (FESEM), Energy Dispersive Spectroscopy (EDS), Transmission Electron Microscopy (TEM), High Resolution Transmission Electron Microscopy (HRTEM), Fourier Transform Infrared Spectroscopy (FTIR), Ultraviolet–visible spectroscopy (UV-vis.), and X Ray Diffraction (XRD) analysis. A linear current versus potential responses relation was obtained in a concentration range of L-lactic acid of 0.30∼2.40 mM at differential pulse voltammetric (DPV) analysis in a pH 7.0 buffer medium and resulted concentration range was defined as the dynamic detection range (LDR) for L-lactic acid analysis. The L-lactic acid sensor sensitivity (0.4529 µAµM -1 cm -2 ), detection limit (LOD; 22.36±1.12 µM), and limit of detection (LOQ; 79.88 µM) were obtained. Besides this, the sensor reproducibility and response time were found to be reliable. Finally, the assembled sensor probe was validated by the testing of real samples, which exhibited acceptable and satisfied results. It is introduced a new route for the detection of chemicals using novel nanocomposite materials by electrochemical approach for the safety of healthcare fields in a broad scales.