GW26-e2102 Gut microbiota alter cholesterol metabolism and regulate NPC1L1 by inducing the expression of Cyp7a1

To investigate the function of intestinal bacteria in NPC1L1 mediating cholesterol. Germ Free mice and Specified Pathogen Free (SPF) mice were treated with western diet and ezetimibe, cholesterol metabolism related data were tested in different ways. Metagenome Sequencing was used to test the