Overview of the QuEChERS Method for Sample's extraction in different food, environmental and biological samples.

The QuEChERS method is a sample preparation technique that was first applied in analytical chemistry to extract and purify pesticide residues in food. QuEChERS is an acronym for (quick, easy, cheap, effective, rugged, and safe). The method has expanded in recent years to accommodate matrices other than food and environmentally with different analytes other than pesticides. This paper's primary goal was to describe the evolution of QuEChERS applications. The number of scientific articles produced annually rose steadily which demonstrated that research using the QuEChERS approach is still relevant 20 years later. The most productive and cooperative nations in the area were China. The original QuEChERS procedure was based on an initial single-phase extraction with acetonitrile. A liquid-liquid partition was created by adding excess salts and buffers to the extract. QuEChERS method demonstrate how the method has expanded into great applications like Food and feed analysis, Biological analysis, and Environmental analysis. The method was effective for the extraction of many groups of compounds, including pesticides, pharmaceuticals, mycotoxins, phthalates, preservatives and synthetic sweeteners in a wide variety of complex matrices.