鼻病毒
临床试验
病毒学
蛋白酶
医学
呼吸系统
体外
免疫学
病毒
生物
酶
内科学
生物化学
标识
DOI:10.1016/s1471-4892(01)00083-2
摘要
Rhinoviruses are the most common causes of viral respiratory infections and complications caused by viral respiratory infections in patients with underlying lung disease. Major recent therapeutic advances include the development of capsid-function inhibitors (pleconaril), inhibitors of 3C protease (AG7088), and recombinant soluble intercellular adhesion molecule (sICAM)-1, all of which exhibit potent antirhinoviral activity in vitro and varying activity in clinical trials. Pleconaril and AG7088 have shown the most promise and are the most advanced in clinical trials.
科研通智能强力驱动
Strongly Powered by AbleSci AI