医学
结直肠癌
新辅助治疗
重症监护医学
放射治疗
肿瘤科
内科学
癌症
乳腺癌
作者
Shehara Mendis,Yat Hang To,Jeanne Tie
标识
DOI:10.1016/j.clcc.2021.11.002
摘要
Locally advanced rectal cancers (LARC) are the subject of a rapidly evolving treatment paradigm. The critical timepoints where management decisions are required during the care of the LARC patient are: prior to the institution of any treatment, post neoadjuvant therapy and post-surgery. This article reviews the clinical, imaging, blood-based, tissue-based, and molecular biomarkers that can assist clinicians at these timepoints in the patient's management, in prognosticating for their LARC patients or in predicting responses to therapy in the multi-modality neoadjuvant treatment era.
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