Evaluation of Biocompatibility of Bioactive Glass, Bioactive Glass-Hydroxyapatite and Mineral Trioxide Aggregate-An in Vitro Study

2 Abstract: The aim of this study is to evaluate the biocompatibility of Bioactive glass (BG) and Bioactive glass- Hydroxyapatite (BG-HA) in comparison to Mineral Trioxide Aggregate (MTA). The biocompatibility was assessed by estimation of cell count and alkaline phosphatase activity on Osteoblastic cell line (Saos-2). The biocompatibility was statistically analyzed using one way ANOVA followed by Tukey HSD Post hoc test. The study showed that Bioactive glass -Hydroxyapatite was less cytotoxic than BG and MTA and not significantly different from each other. Bioactive glass-hydroxyapatite showed better biocompatibility compared to bioactive glass and Mineral Trioxide Aggregate.