Photodynamic Therapy with Aminolevulinic Acid and Iron Chelators: A Clinical Example of Redox Signaling

This chapter contains sections titled: Photodynamic Therapy The Development of Photodynamic Therapy Aminolevulinic Acid Photodynamic Therapy Heme Biosynthesis and Regulation During ALA-PDT Iron and the Enhancement of ALA-PDT Redox Signaling in Photodynamic Therapy after Light Irradiation Photosensitizers as Reactive Oxygen Species Generators in Redox Research Reactive Oxygen Species Generation and Signaling in Clinical Photodynamic Therapy Apoptosis in Photodynamic Therapy Subcellular Localization of Reactive Oxygen Species Production Changes in Transcription Factor and Protein Levels Following Photodynamic Therapy Iron and Iron Chelation Post Light Activation of Photosensitizer Vascular Damage, Hypoxia and Hypoxia Inducible Factor Conclusion References