分析物
荧光
转导(生物物理学)
化学
纳米技术
分子
信号(编程语言)
组合化学
材料科学
计算机科学
有机化学
色谱法
生物化学
量子力学
物理
程序设计语言
出处
期刊:Acs Symposium Series
日期:1993-10-20
被引量:357
摘要
Each new ability to visualize analyte concentrations in real-time portends the fabrication of new sensors. Potential applications include fiber optic-based remoting sensing of solution species and the monitoring of concentrations within living cells. A fluorescent chemosensor is a compound of abiotic origin that complexes to an analyte reversibly with concomitant fluorescence signal transduction. Such chemosensors have been used for fluorimetric metal ion determination for over 100 years. The advent of ligand engineering has introduced a more systematic approach to the design of chemosensors with new selectivities and signal transduction schemes. The technological driving force to achieve useful chemosensors will stimulate investigation of new topics in molecule recognition, fluorescent signal transduction, and their intersection.
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